Table 2.

Eligibility criteria for the WONDER-01 trial

Inclusion criteria	Exclusion criteria
Patients with WON defined by the revised Atlanta classification [2]	WON inaccessible via the EUS-guided approach
The longest diameter of WON is 4 cm or larger	A LAMS in situ
Patients requiring drainage for WON	Coagulopathy (platelet count < 50,000/mm3 or PT-INR > 1.5)
Patients with symptoms due to WON (e.g. infection, GI symptoms, or jaundice)	Antithrombotic agents cannot be discontinued according to the JGES guideline [29]
Patients aged 18 years or older	Patients who do not tolerate endoscopic procedures
Patients or their representatives provide informed consent	Pregnant women
	Patients considered inappropriate for inclusion by the investigators

Abbreviations: EUS Endoscopic ultrasound, JGES Japan Gastroenterological Endoscopy Society, LAMS Lumen-apposing metal stent, PT-INR, Prothrombin time international normalised ratio, WON Walled-off necrosis