Killerby 2020.

Study characteristics
Notes	English title Characteristics associated with hospitalization among patients with COVID‐19 ‐ metropolitan Atlanta, Georgia, March‐April 2020  Study setting Start of study recruitment (MM/YYYY): 03/2020 End of study recruitment (MM/YYYY): 04/2020 Study design: Registry data Study centre(s): Multiple centres/clinics/areas within a country Number of centres/clinics/areas: Six acute care hospitals and associated outpatient clinics  Study setting: Outpatient and inpatient Number of participants recruited: 531 Sampling method: Consecutive participants Participants Female participants (absolute number): 303 Age measure, value: NR Inclusion criteria: Hospitalised patients aged ≥ 18 years who were hospitalised with laboratory‐confirmed COVID‐19 (defined as a positive real‐time reverse transcription–polymerase chain reaction [RT‐PCR] test result for SARS‐CoV‐2) during March 1–30 and non‐hospitalised patients aged ≥ 18 years with laboratory‐confirmed COVID‐19 during March 1–April 7 Exclusion criteria: Persons lacking a healthcare visit during which a medical history could be recorded were excluded from analyses and if they stayed for observation or died in an ED. And persons lacking a healthcare visit during which a medical history could be recorded were excluded from analyses. Smoking frequency: 91 Diabetes frequency: 111 Hypertension frequency: 243 Cardiovascular disease frequency: 20 Asthma frequency: NR Chronic obstructive pulmonary disease frequency: NR Other pulmonary disease frequency: 101 Immunosuppression frequency: 15 Chronic kidney disease frequency: 45 Cancer frequency: 34 Steroid administration frequency: NR Supplemental oxygen administration frequency: NR Other treatments (frequency): NR Prognostic factor(s) Study’s definition for obesity: BMI ≥ 30 kg/m2 The time when obesity has been measured: Before disease or right at presentation Main variable used for determination of obesity: BMI Threshold used for definition of obesity: 30 Obesity frequency (absolute number): 227 Prognostic factor(s): BMI ≥ 30 kg/m2 Outcome(s) Hospitalisation Outcome (prognostic factor) Hospitalisation (BMI ≥ 30 kg/m2) Follow‐up Number of patients followed completely for the outcome: 531 Number of obese patients followed completely for the outcome: 227 Number of non‐obese patients followed completely for the outcome: 209 Univariable unadjusted analysis for obesity Effect measure for obesity: NR Effect measure value (95% CI), P value: 1.82 (1.2, 2.57), NR Multivariable analysis for obesity Modelling method: Logistic regression The set of prognostic factors used for adjustment: NR Effect measure for obesity: Odds ratio  Effect measure value (95% CI), P value: 1.9 (1.1, 3.3), NR
Item	Authors' judgement	Support for judgement
Study Participation	Yes	Appendix 3
Study Attrition Hospitalisation	Unclear	Appendix 3
Prognostic Factor Measurement	No	Appendix 3
Outcome Measurement Hospitalisation	Yes	Appendix 3
Confounding Bias Hospitalisation	Yes	Appendix 3
Statistical Analysis Bias	Yes	Appendix 3