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. 2023 May 24;2023(5):CD015201. doi: 10.1002/14651858.CD015201

Omrani 2020.

Study characteristics
Notes English title
The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation‐wide cohort study
Study setting
Start of study recruitment (MM/YYYY): 02/2020
End of study recruitment (MM/YYYY): 04/2020
Study design: Retrospective cohort
Study centre(s): Multiple centres/clinics/areas within a country
Number of centres, clinics or areas: NR
Study setting: Outpatient and inpatient
Number of participants recruited: 5000
Sampling method: Consecutive participants
Participants
Female participants (absolute number): 564
Age measure, value: Median (IQR), 35 (28, 43)
Inclusion criteria: The first consecutive 5000 patients with RT‐PCR‐confirmed COVID‐19 who would complete 60 days of follow up from date of diagnosis
Exclusion criteria: NR
Smoking frequency: NR
Diabetes frequency: 470
Hypertension frequency: 476
Cardiovascular disease frequency: 61
Asthma frequency: NR
Chronic obstructive pulmonary disease frequency: NR
Other pulmonary disease frequency: 156
Immunosuppression frequency: NR
Chronic kidney disease frequency: 44
Cancer frequency: 31
Steroid administration frequency: NR
Supplemental oxygen administration frequency: NR
Other treatments (frequency): NR
Prognostic factor(s)
Study’s definition for obesity: Body mass index (BMI), defined as body weight in kilograms divided by squared height in metres
The time when obesity has been measured: Before disease or right at presentation
Main variable used for determination of obesity: BMI
Threshold used for definition: Not applicable
Obesity frequency (absolute number): NR
Prognostic factor(s): BMI (per 1 kg/m2 increase)
Outcome(s)
ICU admission
Outcome (prognostic factor)
ICU admission (BMI (per one kg/m2 increase))
Follow‐up
Number of patients followed completely for the outcome: 1409
Number of obese patients followed completely for the outcome: NR
Number of non‐obese patients followed completely for the outcome: NR
Univariable unadjusted analysis for obesity
Effect measure for obesity: Odds ratio
Effect measure value (95% CI), P value: 1.067 (1.033, 1.102), < 0.001
Multivariable analysis for obesity
Modelling method: Logistic regression
The set of prognostic factors used for adjustment: The final multivariable logistic regression model included age, male sex, body mass index (BMI), defined as body weight in kilograms divided by squared height in metres, and co‐existing diabetes mellitus, systemic hypertension, coronary artery disease, chronic liver disease, and chronic kidney disease.
Effect measure for obesity: Odds ratio
Effect measure value (95% CI), P value: 1.067 (1.027, 1.108), 0.001
 
Item Authors' judgement Support for judgement
Study Participation Yes Appendix 3
Study Attrition
ICU admission No Appendix 3
Prognostic Factor Measurement Yes Appendix 3
Outcome Measurement
ICU admission Yes Appendix 3
Confounding Bias
ICU admission Yes Appendix 3
Statistical Analysis Bias Yes Appendix 3