Rossi 2020.

Study characteristics
Notes	English title Obesity as a risk factor for unfavourable outcomes in critically ill patients affected by Covid‐19 Study setting Start of study recruitment (MM/YYYY) 03/2020 End of study recruitment (MM/YYYY) 03/2020 Study design prospective cohort Study centre(s) single centres/clinics/areas within a country Number of centres/clinics/areas 1 Study setting inpatient Number of participants recruited 95 Sampling method consecutive participants Participants Female participants (absolute number), 17 Age measure, value mean (standard deviation), 62.46 (11.74) Inclusion criteria NR Exclusion criteria NR Smoking NR Diabetes (absolute number), 18 Hypertension (absolute number), 44 Cardiovascular diseases (absolute number), 5 Please indicate if additional information is available  IHD + HF Asthma (unspecified), NR Chronic obstructive pulmonary disease (unspecified), NR Other pulmonary diseases (unspecified), NR Please indicate if additional information is available  NR Immunosuppression (absolute number), 19 Please indicate if additional information is available NR Chronic kidney disease (absolute number), 15 Cancer (absolute number), 3 Steroid administration (unspecified), NR Supplemental oxygen (unspecified), NR Differential values for various oxygenation methods (if indicated) NR Other treatment NR Dose if applicable NR Duration if applicable NR Percentage received this treatment NR Prognostic factor(s) Study’s definition for obesity BMI in normal weight subjects (BMI < 27 kg/m2), overweight (BMI between 27 and 29.9 kg/m2) and subjects with obesity (BMI > 30) The time when obesity has been measured before disease or right at presentation Main variable used for determination of obesity BMI Threshold used for definition of obesity  30 Measure of frequency absolute number Frequency value 35 How many eligible outcomes reported? 1 How many eligible outcomes reported? 1 Outcome(s) mortality Outcome (prognostic factor) Outcome NR Prognostic factor (category):  NR Follow‐up Number of patients followed completely for this outcome  95 Number of obese patients followed completely for this outcome  35 Number of non‐obese patients followed completely for this outcome  60 Univariable (unadjusted) analysis for obesity Effect measure for obesity NR Effect measure value (95% CI) NR Multivariable (adjusted) analysis for obesity Modelling method logistic regression The set of prognostic factors used for adjustment age, sex, smoking habit, hypertension, diabetes, congestive heart failure, chronic renal failure, immunodepression, cancer, chronic obstructive pulmonary disease, coronary heart disease Effect measure for obesity hazard ratio Effect measure value (95% CI) 5.3 (1.26, 22.34)
Item	Authors' judgement	Support for judgement
Study Participation	Unclear	Appendix 3
Study Attrition Mortality	Yes	Appendix 3
Prognostic Factor Measurement	Yes	Appendix 3
Outcome Measurement Mortality	Yes	Appendix 3
Confounding Bias Mortality	Yes	Appendix 3
Statistical Analysis Bias	Yes	Appendix 3