Figure 4. LIN28B in Breast Cancer and Breast Cancer Metastasis. (A) Breast cancer subtype distribution among the whole breast cancer entity [91], and the LIN28B upregulation, including amplification and high mRNA expression, in a breast cancer cohort of 463 patients (TCGA, Nature 2012, [92]) [7,8]. (B) Illustration of the most common metastatic sites in breast cancer patients and the LIN28B or let-7 feature in the primary breast tumor contributing to metastasis formation at specific sites [89,90,94–96]. Created with BioRender.com.
