Table 1. The correlation between RNF43 expression and clinicopathologic characteristics of patients with clear cell renal cell carcinoma in cohort 1.

Characteristic	RNF43		Sum (193)	P* value
	Low expression (n = 86)	High expression (n = 107)
Age				0.194
<60	39	59	98
≥60	47	48	95
Gender				0.124
Male	52	77	129
Female	34	30	64
WHO/ISUP Grading				0.070
I–II	49	75	124
III–IV	37	32	69
TNM stage				<0.001*
I–II	59	99	158
III–IV	27	8	35
SSIGN				<0.001*
0–4	65	101	166
≥5	21	6	27
YAP				<0.001*
Low expression	37	77	114
High expression	49	30	79

Note: *: Statistical significance was calculated by chi-square test or fisher’s exact test for categorical/binary measures.