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. 2022 Aug 1;29(3):159–174. doi: 10.32604/or.2022.03458

Table 3. The correlation between expressions of RNF43, YAP and clinicopathologic characteristics of patients with clear cell renal cell carcinoma in cohort 1.

Characteristic RNF43/YAP expression P* value
RNF43high YAPlow (n = 77) RNF43low YAPlow (n = 37) RNF43high YAPhigh (n = 30) RNF43low YAPhigh (n = 49) Sum(193)
Age 0.165
<60 46 19 13 20 98
≥60 31 18 17 29 95
Gender 0.022*
Male 59 18 18 34 129
Female 18 19 12 15 64
WHO/ISUP Grading 0.008*
I–II 60 19 15 30 124
III–IV 17 18 15 19 69
TNM stage <0.001*
I–II 74 31 25 28 158
III–IV 3 6 5 21 35
SSIGN <0.001*
0–4 75 30 26 35 166
≥5 2 7 4 14 27

Note: *: Statistical significance was calculated by chi-square test or fisher’s exact test for categorical/binary measures and ANOVA for continuous measures.