Table 3. The correlation between expressions of RNF43, YAP and clinicopathologic characteristics of patients with clear cell renal cell carcinoma in cohort 1.
Characteristic | RNF43/YAP expression | P* value | ||||
---|---|---|---|---|---|---|
RNF43high YAPlow (n = 77) | RNF43low YAPlow (n = 37) | RNF43high YAPhigh (n = 30) | RNF43low YAPhigh (n = 49) | Sum(193) | ||
Age | 0.165 | |||||
<60 | 46 | 19 | 13 | 20 | 98 | |
≥60 | 31 | 18 | 17 | 29 | 95 | |
Gender | 0.022* | |||||
Male | 59 | 18 | 18 | 34 | 129 | |
Female | 18 | 19 | 12 | 15 | 64 | |
WHO/ISUP Grading | 0.008* | |||||
I–II | 60 | 19 | 15 | 30 | 124 | |
III–IV | 17 | 18 | 15 | 19 | 69 | |
TNM stage | <0.001* | |||||
I–II | 74 | 31 | 25 | 28 | 158 | |
III–IV | 3 | 6 | 5 | 21 | 35 | |
SSIGN | <0.001* | |||||
0–4 | 75 | 30 | 26 | 35 | 166 | |
≥5 | 2 | 7 | 4 | 14 | 27 |
Note: *: Statistical significance was calculated by chi-square test or fisher’s exact test for categorical/binary measures and ANOVA for continuous measures.