Table 4. The correlation between expressions of RNF43, YAP and clinicopathologic characteristics of patients with clear cell renal cell carcinoma in cohort 2.
Characteristic | RNF43/YAP expression | P* value | ||||
---|---|---|---|---|---|---|
RNF43high YAPlow (n = 70) | RNF43low YAPlow (n = 18) | RNF43high YAPhigh (n = 21) | RNF43low YAPhigh (n = 18) | Sum (127) | ||
Age | 0.632 | |||||
<60 | 34 | 8 | 8 | 6 | 56 | |
≥60 | 36 | 10 | 13 | 12 | 71 | |
Gender | 0.328 | |||||
Male | 53 | 12 | 19 | 13 | 97 | |
Female | 17 | 6 | 2 | 5 | 30 | |
WHO/ISUP Grading | 0.008* | |||||
I–II | 52 | 12 | 11 | 6 | 81 | |
III–IV | 18 | 6 | 10 | 12 | 46 | |
TNM stage | <0.001* | |||||
I–II | 70 | 15 | 20 | 13 | 118 | |
III–IV | 0 | 3 | 1 | 5 | 9 | |
SSIGN | <0.001* | |||||
0–4 | 70 | 13 | 20 | 15 | 118 | |
≥5 | 0 | 5 | 1 | 3 | 9 |
Note: *: Statistical significance was calculated by chi-square test or fisher’s exact test for categorical/binary measures and ANOVA for continuous measures.