Table S1. Pre-BCG biopsies raw data.
| Patient | Gender | Age | Pathological stage | Histological grade | GATA-3 (mean) | T-Bet (mean) | G/T | Eo count (mean) | Eo dgn (max) | Eo count *Eo dgn | Th2- score | BCG response | Time to relapse/follow-up (months) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 56 | pT1 | HG | 4,000 | 1,250 | 3,200 | 1,38 | 1 | 1,38 | 4,58 | NR | 56 |
| 2 | M | 71 | pT1 | HG | 31,875 | 134,000 | 0,238 | 3,88 | 1 | 3,88 | 4,11 | NR | 51 |
| 3 | M | 56 | pTa | HG | 12,125 | 20,000 | 0,606 | 38,75 | 2 | 77,50 | 78,11 | NR | 8 |
| 4 | M | 73 | pTa + Cis | LG | 4,250 | 3,000 | 1,417 | 9,38 | 1 | 9,38 | 10,79 | R | >36 |
| 5 | M | 77 | pTa | HG | 109,125 | 9,875 | 11,051 | 0,25 | 1 | 0,25 | 11,30 | R | 9 |
| 6 | M | 76 | pT1 | HG | 0,500 | 2,875 | 0,174 | 28,50 | 1 | 28,50 | 28,67 | R | >69 |
| 7 | F | 65 | pT1 | HG | 30,875 | 0,500 | 61,750 | 7,50 | 1 | 7,50 | 69,25 | R | >70 |
| 8 | F | 60 | pT1 | HG | 194,000 | 132,625 | 1,463 | 96,50 | 2 | 193,00 | 194,46 | R | >71 |
| 9 | M | 62 | pT1 | HG | 24,000 | 0,125 | 192,000 | 1,13 | 1 | 1,13 | 193,13 | R | >60 |
| 10 | M | 61 | pT1 | HG | 5,500 | 3,000 | 1,833 | 28,00 | 2 | 56,00 | 57,83 | R | >55 |
| 11 | F | 44 | pT1 | HG | 0,875 | 5,875 | 0,149 | 0,63 | 1 | 0,63 | 0,77 | R | >9 |
| 12 | M | 70 | pT1 + Cis | HG | 29,750 | 4,375 | 6,800 | 9,38 | 1 | 9,38 | 16,18 | R | >98 |
| 13 | M | 56 | pT1 | HG | 38,375 | 1,750 | 21,929 | 4,75 | 1 | 4,75 | 26,68 | NR | 6 |
| 14 | M | 67 | pT1 | HG | 59,000 | 0,125 | 472,000 | 94,00 | 2 | 188,00 | 660,00 | R | >15 |
| 15 | F | 52 | pT1 | HG | 12,000 | 0,125 | 96,000 | 3,88 | 1 | 3,88 | 99,88 | R | >84 |
| 16 | M | 66 | pT1 | HG | 0,625 | 0,500 | 1,250 | 0,88 | 1 | 0,88 | 2,13 | R | >9 |
| 17 | M | 61 | pT1 | HG | 19,000 | 9,250 | 2,054 | 3,25 | 1 | 3,25 | 5,30 | R | >35 |
| 18 | F | 57 | pT1 | HG | 6,000 | 1,375 | 4,364 | 22,88 | 2 | 45,75 | 50,11 | R | >14 |
| 19 | M | 52 | Cis | HG | 27,875 | 5,750 | 4,848 | 1,25 | 1 | 1,25 | 6,10 | NR | 26 |
| 20 | M | 70 | pT1 | HG | 8,875 | 17,000 | 0,522 | 38,50 | 2 | 77,00 | 77,52 | R | >37 |
| 21 | F | 53 | pT1 | LG | 27,500 | 2,250 | 12,222 | 2,13 | 1 | 2,13 | 14,35 | NR | 6 |
| 22 | F | 70 | pT1 | LG | 2,000 | 0,625 | 3,200 | 0,38 | 1 | 0,38 | 3,58 | NR | 27 |
| 23 | F | 61 | pTa | LG | 0,750 | 7,125 | 0,105 | 1,63 | 1 | 1,63 | 1,73 | NR | 11 |
| 24 | M | 68 | pTa | LG | 0,375 | 0,125 | 3,000 | 0,00 | 0 | 0,00 | 3,00 | NR | 7 |
| 25 | F | 62 | pT1 | HG | 82,250 | 0,125 | 658,000 | 67,75 | 2 | 135,50 | 793,50 | R | >120 |
| 26 | M | 68 | pT1 | HG | 6,125 | 2,625 | 2,333 | 21,88 | 2 | 43,75 | 46,08 | NR | 7 |
| 27 | M | 72 | T1 | HG | 13,000 | 0,125 | 104,000 | 48,13 | 2 | 96,25 | 200,25 | R | >47 |
| 28 | M | 82 | Cis | HG | 48,000 | 13,875 | 3,459 | 6,88 | 2 | 13,75 | 17,21 | R | >41 |
| 29 | F | 67 | pTa | HG | 85,875 | 5,375 | 15,977 | 12,25 | 2 | 24,50 | 40,48 | NR | 15 |
| 30 | M | 72 | pT1 | HG | 101,125 | 1,500 | 67,417 | 4,88 | 0 | 0,00 | 67,42 | R | >30 |
| 31 | F | 31 | pT1 | LG | 67,875 | 18,000 | 3,771 | 1,00 | 1 | 1,00 | 4,77 | R | >17 |
| 32 | M | 74 | pT1 | HG | 79,875 | 8,375 | 9,537 | 41,13 | 1 | 41,13 | 50,66 | R | >32 |
Note: F = female; M = male; Grade: HG = high grade; LG = Low grade; R = BCG responder; NR = BCG non-responder; Th2-score = G/T (Eo count*Eo dgn).