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Germline probability in 22 genes in which pathogenic germline variants were identified. Germline variants in uncertain, low, or recessive alleles in APC, CHEK2, and FH were not included in the numerator of the germline probability calculation: APC low-penetrance allele variant c.3920T > A (p.I1307K). CHEK2 variant allele of uncertain penetrance c.470T > C (p.I157T), and FH recessive allele variant c.1431_1433dupAAA (p.K477dup).
