Table 1. Selected combinations of CA19-9 with other biomarkers.
Combination of biomarkers | Sensitivity | Specificity | Pub. date | Cohorts |
---|---|---|---|---|
CA19-9+CA125+LAMC2 | 84.7 | 89.2 | 2014 | PDAC vs. benign controls |
CA 19-9+CA 242 | 89 | 75 | 2015 | PC vs. benign and healthy controls |
CA 19-9+CA 125+CEA+CA242 | 90 | 94 | 2015 | PC vs. healthy controls |
CA19-9+5MC+H2A1.1+H2AZ+H3K4Me2 | 92 | 90 | 2015 | PC vs. benign and healthy controls |
CA 19-9+albumin+IGF-1 | 94 | 95 | 2016 | PDAC vs. CHP and healthy controls |
CA 19-9+MUC5A | 75 | 83 | 2017 | PC vs. CHP and benign controls |
CA 19-9+CEA+HGF+OPN+ctDNA | 64 | 99.5 | 2017 | PDAC vs. healthy controls |
CA 19-9+THBS2 | 87 | 98 | 2017 | PDAC vs. benign and healthy controls |
CA 19-9+MDMs | 92 | 92 | 2021 | PDAC vs. healthy controls |
Note: PDAC, pancreatic ductal adenocarcinoma; PC, pancreatic cancer; CHP, chronic pancreatitis; benign, benign pancreatic disease.