FIGURE 2. Constructing of the prognostic signature. (A, B) Lasso regression to construct prognostic signature, the curve converged when Lamda was eight. (C) Risk score of training cohort. (D) Risk score of internal validation cohort. (E) The correlation between risk score and survival status of patients in training cohort. (F) The correlation between risk score and survival status of patients in internal validation cohort. (G) Heat map of eight model genes expression in training cohort. (H) Heat map of eight model genes expression in internal validation cohort.