FIGURE 2. CCDC183-AS1 downregulation restricts the aggressiveness of BC cells. (A) The expression pattern of CCDC183-AS1 in BC cell lines. ***p < 0.001 (n = 3) vs. MCF-7. (B) Two siRNAs targeting CCDC183-AS1 were delivered into BC cells. The efficiency of si-CCDC183-AS1 transfection was detected by qRT-PCR. ***p < 0.001 (n = 3) vs. si-NC. (C) CCK-8 assay examined the proliferative ability of BC cells when CCDC183-AS1 was knocked down. ***p < 0.001 (n = 3) vs. si-NC. **p < 0.01 (n = 3) vs. si-NC. (D) Colony formation in CCDC183-AS1-silenced BC cells. ***p < 0.001 (n = 3) vs. si-NC. (E) Migration and invasion (×200 magnification) of BC cells after CCDC183-AS1 deficiency. ***p < 0.001 (n = 3) vs. si-NC.
