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. 2023 May 5;34(6):ar57. doi: 10.1091/mbc.E22-11-0507

TABLE 2:

Parameters varied in stochastic reaction-diffusion-dynamics model: numerical values of SRDDM parameters, which were varied and the simulation output.

Figure Case study Varied model parameters
Parameter Value Findings
3 No chromosome arms K KT,r 0.83 pN/nm 62.5% amphitelic, 0% merotelic
83.0 pN/nm 50% amphitelic, 25% merotelic
333.0 pN/nm 25% amphitelic, 0% merotelic
Short chromosome arms (5 μm) K KT,r 0.83 pN/nm 75% amphitelic, 0% merotelic
83.0 pN/nm 62.5% amphitelic, 0% merotelic
333.0 pN/nm 50% amphitelic, 0% merotelic
Long chromosome arms (8 μm) K KT,r 0.83 pN/nm 50% amphitelic, 12.5% merotelic
83.0 pN/nm 62.5% amphitelic,12.5% merotelic
333.0 pN/nm 62.5% amphitelic, 0% merotelic
4 Kinetochore surface area A KT 0.03 μm2 0% amphitelic, 25% merotelic
0.15 µm2 62.5% amphitelic, 0% merotelic
0.36 μm2 25% amphitelic, 12.5% merotelic