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Number of gray white nodules in mice on days 58 and 112.
| Group | Number of animals occurred |
|
|---|---|---|
| Day 58 | Day 112 | |
| Adjuvant control group | 3/17（ M 2/8，F 1/9） | 3/12（M 0/6，F 3/6） |
| Vaccine low dose group | 13/18（M 6/9，F 7/9） | 7/12（M 4/6，F 3/6） |
| Vaccine medium dose group | 10/18（M 3/9，F 7/9） | 4/12（M 3/6，F 1/6） |
| Vaccine high dose group | 12/18（M 6/9，F 6/9） | 6/12（M 2/6，F 4/6） |
