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. 2023 May 10;17:1106350. doi: 10.3389/fnins.2023.1106350

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Copyright © 2023 Martín-Martín, Planchuelo-Gómez, Guerrero, García-Azorín, Tristán-Vega, de Luis-García and Aja-Fernández.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of TBSS analysis: statistically significant clusters of voxels distinguishing between DTI and AMURA approaches. Mean FA image at the background, FA skeleton colored in blue and significant ROIs colored in red-yellow. (A) Episodic Migraine (EM) vs. Healthy Controls (HC): merged AMURA measures (RTOP, RTAP, APA, qMSD, ϒ^1/2, and DiA). (B) CM vs. EM: merged DTI (AD and MD) and AMURA (RTPP and ϒ^1/2) measures. DTI measures do not detect any significant ROI either in EM vs. HC nor CM vs. HC. Green circles showed the areas where AMURA measures showed differences in group comparisons where the DTI ones did not.