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Effects of arginase on HIV replication in macrophages. HIV replication is represented by the sum, at the end of the culture of an individual well, of the RT activities of each time point of medium exchange (every 2 or 3 days). Bars indicate the mean (±SD) of RT activity of three independent wells. Statistical analysis was performed using the nonparametric Mann-Whitney U test. ∗, significant difference between treated and untreated HIV-infected cultures (P < 0.05).
