Table 1. Demographic and clinical characteristics of SSc patients.
| Limited cutaneous SSc (n=115) | Diffuse cutaneous SSc (n=141) | Total SSc group (n=256) | p | ||||||||||
| % | Mean±SD | Median | Range | % | Mean±SD | Median | Range | % | Mean±SD | Median | Range | ||
| Age (year) | 50.8±12.9 | 51.5±12.2 | 50.9±12.4 | 0.653 | |||||||||
| Disease duration (year) | 8 | 1-35 | 10 | 0-46 | 9.75 | 0-46 | 0.001 | ||||||
| Time since diagnosis (year) | 4 | 0-24 | 6.88 | 0-35 | 5.00 | 0-35 | <0.001 | ||||||
| Sex | |||||||||||||
| Female | 92.2 | 92.1 | 92.2 | 1.00 | |||||||||
| Body mass index (kg/m2) | 28.3±4.7 | 25.9±5.6 | 27.0±5.2 | <0.001 | |||||||||
| Education | 0.275 | ||||||||||||
| No formal education | 25.2 | 34 | 30.1 | ||||||||||
| Primary school | 51.3 | 45.4 | 48 | ||||||||||
| Elementary school | 9.6 | 5.7 | 7.4 | ||||||||||
| High school | 9.6 | 7.1 | 8.2 | ||||||||||
| University | 4.3 | 7.8 | 6.3 | ||||||||||
| Raynaud phenomenon | 87.9 | 90.7 | 89.5 | 0.542 | |||||||||
| Abnormal nail fold capillaries | 74.1 | 80.7 | 77.7 | 0.23 | |||||||||
| Digital ulcers | 9.6 | 29.8 | 20.7 | <0.001 | |||||||||
| Digital pitting | 15.8 | 56 | 38 | <0.001 | |||||||||
| Telangiectasia | 38.8 | 63.6 | 52.3 | <0.001 | |||||||||
| Sclerodactyly | 58.6 | 89.3 | 75.4 | <0.001 | |||||||||
| Calcinosis | 7.8 | 12.1 | 10.2 | 0.301 | |||||||||
| Arthritis | 23.3 | 22.1 | 22.7 | 0.88 | |||||||||
| Contracture | 20.7 | 40.7 | 31.6 | 0.001 | |||||||||
| Tendon friction rubs | 15.5 | 26.4 | 21.5 | 0.046 | |||||||||
| Modified Rodnan skin score | 7 | 0-23 | 24.5 | 9-46 | 16 | 0-46 | <0.001 | ||||||
| Dysphagia | 31.9 | 52.9 | 43.4 | 0.001 | |||||||||
| Dyspnea | 32.8 | 51.4 | 43 | 0.003 | |||||||||
| Lung fibrosis on HRCT | 28.1 | 60.7 | 46.1 | <0.001 | |||||||||
| Pulmonary artery pressure | 25 | 15-80 | 30 | 15-65 | 28 | 15-80 | 0.005 | ||||||
| Forced vital capacity | 89.5 | 26-100 | 84 | 37-100 | 85 | 26-100 | 0.013 | ||||||
| DLCO | 84 | 21-100 | 80.5 | 17-100 | 82 | 17-100 | 0.131 | ||||||
| Disease activity score | 1 | 0-8.5 | 2.5 | 0-10 | 2 | 0-10 | <0.001 | ||||||
| 6 Minute Walking Distance (m) | 435 | 10-750 | 392.5 | 30-640 | 400 | 10-750 | <0.001 | ||||||
| ESR (mm/h) | 19.5 | 3-80 | 19.5 | 3-74 | 19.5 | 3-80 | 0.482 | ||||||
| C-reactive protein (mg/dL) | 0.39 | 0.03-5 | 0.37 | 0-5 | 0.37 | 0-5 | 0.96 | ||||||
| Anti-nuclear antibody (+) | 89.7 | 86.4 | 87.9 | 0.343 | |||||||||
| Anticentromere (+) | 46.6 | 11.5 | 27.5 | <0.001 | |||||||||
| AntiScl-70 (+) | 28.4 | 51.8 | 41.2 | 0.002 | |||||||||
| SSc: Systemic sclerosis; SD: Standard deviation; HRCT: High resolution computed tomography; DLCO: Single breath diffusing capacity for carbon monoxide; ESR: Erythrocyte sedimentation rate. | |||||||||||||