Table 3. Diagnostic performance of pro-apoptotic autophagy agent (Bax and Bad) in discriminating SLE from control subjects.

Test	Cut-off	Sensitivity (%)	95% CI	Specificity (%)	95% CI	PPV (%)	NPV (%)
Bax/β-actin	<0.66	27	0.1607 to 0.3966	90	0.7949 to 0.9624	37	85
Bad/β-actin	<0.80	43	0.3059 to 0.5676	92	0.8161 to 0.9724	53	88
Index	<16.36	35	0.2313 to 0.4840	92	0.8161 to 0.9724	48	87
Index= (Bax*Bad)/β-actin, SLE: Systemic lupus erythematosus; CI: Confidence interval; PPV: Positive, predictive value; NPV: Negative predictive value.