Figure 2. Genomic and evolutionary characteristics of elusive genes.
Distributions of non-synonymous, synonymous, and intronic nucleotide substitution rates, namely KA (a), KS (b), and KI (c) values, respectively, between the human–chimpanzee orthologs of the elusive and non-elusive genes. Distribution of gene length (d) and GC content (e) of the human elusive and non-elusive genes. (f) Distribution of gene density in the genomic regions where the human elusive and non-elusive genes are located. The plots consist of 249 elusive and 5145 non-elusive genes that retained chimpanzee orthologs (a, b), 473 and 4626 of those which harbored introns aligned with the chimpanzee genome (c; see ‘Materials and methods’), and all of the 813 elusive and 8050 non-elusive genes (d–f). Diamonds and bars within violin plots indicate the median and range from the 25th to 75th percentile, respectively.
Figure 2—figure supplement 1. Comparison of KA and KS values between orthologs of the elusive and non-elusive genes.
