Author response table 1. Difference in statistical significances across different elusive gene sets.

Features	Non-significant in theinitial gene set(1,081 elusive genes)	Non-significant in thecurrent gene set(813)	Non-significant in the current gene setexcluding chr19(669)
Gene density in the turkey genome	✓	✓	✓
Gene density in the green anole genome	✓
Gene density in the bamboo shark genome	✓
Gene density in the whale shark genome	✓	✓	✓
KS in avians		✓	✓
KA in avians	✓	✓	✓
KA in sharks	✓	✓	✓
ATAC-seq peak density for GM23338	✓
Lamin B1 ChIP-seq peak density for K562			✓

The other features showed significantly different trends between the elusive and non-elusive genes for all of the elusive gene sets and thus are not included in this table.