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. 2023 May 24. Online ahead of print. doi: 10.1016/j.amjmed.2023.04.040

Table 3.

Symptoms and QOL of respondents by COVID-19 and vaccination status (N = 19,784)

Total (n = 19,784) COVID-19 infection
Number of COVID-19 vaccines
Respondents with COVID-19 (n = 2,397) Respondents without COVID-19 (n = 17,387) 0 (n = 2,562) 1 (n = 120) 2 (n = 2,507) 3 or 4 (n = 14,595)
SSS-8 [IQR] 5 (2-10) 8 (3-14) 5 (2-9) 6 (1-12) 10 (4.5-15.5) 6 (2-11) 5 (2-9)
Stomach or bowel problem 9,119 (46.1) 1,411 (58.9) 7,708 (44.3) 1,207 (47.1) 85 (70.8) 1,170 (46.7) 6,657 (45.6)
Back pain 11,448 (57.9) 1,589 (66.3) 9,859 (56.7) 1,410 (55.0) 84 (70.0) 1,450 (57.8) 8,504 (58.3)
Pain in arms, legs or joints 9,853 (49.8) 1,320 (55.1) 8,533 (49.1) 1,198 (46.8) 75 (62.5) 1,117 (44.6) 7,463 (51.1)
Headache 8,242 (41.7) 1,436 (59.9) 6,806 (39.1) 1,171 (45.7) 79 (65.8) 1,268 (50.6) 5,724 (39.2)
Chest pain or shortness of breath 6,167 (31.2) 1,063 (44.4) 5,104 (29.4) 914 (35.7) 67 (55.8) 822 (32.8) 4,364 (29.9)
Dizziness 5,674 (28.7) 1,002 (41.8) 4,672 (26.9) 863 (33.7) 69 (57.5) 848 (33.8) 3,894 (26.7)
Feeling tired or having low energy 11,918 (60.2) 1,703 (71.1) 10,215 (58.8) 1,519 (59.3) 78 (65.0) 1,611 (64.3) 8,710 (59.7)
Trouble sleeping 10,104 (51.1) 1,424 (59.4) 8,680 (49.9) 1,350 (52.7) 80 (66.7) 1,299 (51.8) 7,375 (50.5)
EQ-5D-5L [IQR] 1.0 (0.8-1.0) 0.9 (0.8-1.0) 1.0 (0.8-1.0) 1.0 (0.8-1.0) 0.9 (0.5-1.0) 1.0 (0.8-1.0) 1.0 (0.8-1.0)
Mobility 2,427 (12.3) 549 (22.9) 1,878 (10.8) 442 (17.3) 48 (40.0) 278 (11.1) 1,659 (11.4)
Self-care 1,327 (6.7) 469 (19.6) 858 (4.9) 320 (12.5) 45 (37.5) 203 (8.1) 759 (5.2)
Usual activity 2,035 (10.3) 529 (22.1) 1,506 (8.7) 410 (16.0) 46 (38.3) 288 (11.5) 1,291 (8.9)
Pain/Discomfort 7,281 (36.8) 928 (38.7) 6,353 (36.5) 973 (38.0) 61 (50.8) 818 (32.6) 5,429 (37.2)
Anxiety/Depression 5,408 (27.3) 890 (37.1) 4,518 (26.0) 871 (34.0) 58 (48.3) 812 (32.4) 3,667 (25.1)

NOTE:

All categorical data are presented as a number (percentage, %) except SSS-8 and EQ-5D-5L, which are presented as the median (interquartile range, IQR).

Abbreviations: QOL, quality of life; COVID-19, coronavirus disease 2019; SSS-8, Somatic Symptom Scale-8; IQR, interquartile range; EQ-5D-5L, EuroQol 5-dimensions 5-levels.