Table S1.

The expression profiles of 25 representative genes in terpenoid backbone biosynthesis, steroid biosynthesis, and steroid hormone biosynthesis pathways.

Gene name	Mean of erinacine S (16 h)	Mean of DMSO (16 h)	Mean of erinacine S (48 h)	Mean of DMSO (48 h)	log2FoldChange (erinacine 16 h/DMSO16 h)	log2FoldChange (erinacine 48 h/DMSO 48 h)	log2FoldChange (erinacine 48 h/erinacine 16 h)
Acat2	361.6090	316.2732	432.7321	327.7989	0.1933	0.4007	0.2590
Acat3	60.5840	51.1709	69.7669	53.6660	0.2436	0.3785	0.2036
Hmgcs1	1143.5020	1028.2884	1434.2570	1169.0247	0.1532	0.2950	0.3268
Hmgcs2	0.0649	0.0488	0.0160	0.0136	0.4110	0.2355	−2.0149
Fdps	778.6338	688.5077	846.9608	607.8225	0.1775	0.4786	0.1214
Mvk	132.1852	119.0552	127.3504	110.7471	0.1509	0.2015	−0.0538
Nsdhl	144.2580	120.0450	149.0973	100.0962	0.2651	0.5749	0.0476
Hsd17b7	28.6533	27.0347	37.3982	29.8658	0.0839	0.3245	0.3843
Cyp51	282.8622	255.7440	334.1518	277.3857	0.1454	0.2686	0.2404
Msmo1	208.4856	186.7944	240.3518	181.1271	0.1585	0.4081	0.2052
Sc5d	88.6097	83.0326	120.8936	88.8171	0.0938	0.4448	0.4482
Dhcr7	160.8497	137.9424	188.6604	131.6858	0.2216	0.5187	0.2301
Soat1	4.8730	4.7322	4.5008	4.7582	0.0423	−0.0802	−0.1146
Soat2	0.6062	0.4746	0.2589	0.1537	0.3531	0.7528	−1.2272
Cel	0.0664	0.0106	0.0001	0.0078	2.6502	−6.2816	−9.3744
Lss	131.1258	114.7167	130.7294	95.8294	0.1929	0.4480	−0.0044
Hsd11b2	0.1506	0.0635	0.0387	0.1238	1.2462	−1.6798	−1.9625
Hsd3b3	0.0001	0.0033	0.0091	0.0001	−5.0522	6.5005	6.5005
Hsd3b2	0.0001	0.0001	0.0061	0.0001	0.0000	5.9384	5.9384
Hsd11b1	0.5163	0.8529	0.7598	0.4879	−0.7241	0.6391	0.5574
Cyp11a1	0.1401	0.0826	0.0702	0.1764	0.7634	−1.3299	−0.9980
Srd5a1	12.0653	10.1539	17.0068	14.9217	0.2488	0.1887	0.4952
Srd5a2	0.1948	0.1165	0.0001	0.0628	0.7420	−9.2936	−10.9279
Akr1c18	0.0414	0.1358	0.0156	0.0497	−1.7133	−1.6746	−1.4113
Cyp21a1	0.0001	0.0163	0.0001	0.0379	−7.3526	−8.5665	0.0000