TABLE I.
Study characteristics. SBP: systolic blood pressure, eGFR: estimated glomerular filtration rate; data are represented as mean±SEM.
Uremic parameters | Sham | CKD | p-valuea | |
---|---|---|---|---|
Baseline | ||||
Creatinine (μmol/l) | 30.6 ± 2.9 | 34.9 ± 4.0 | 0.39 | |
Urea (mmol/l) | 6.7 ± 0.3 | 6.2 ± 0.2 | 0.14 | |
Proteinuria (mg/24h) | 3.4 ± 0.7 | 4.6 ± 1.3 | 0.43 | |
SBP (mmHg) | 130.7 ± 3.5 | 132.3 ± 2.7 | 0.72 | |
eGFR(μl/min) | 2071 ± 124 | 2015 ± 146 | 0.77 | |
Weight (g) | 227 ± 5 | 228 ± 3 | 0.88 | |
Pre implantation | ||||
Creatinine (μmol/l) | 32.9 ± 1.9 | 86.0 ± 5.6 | <0.0001 | |
Urea (mmol/l) | 6.8 ± 0.2 | 16.6 ± 0.6 | <0.0001 | |
Proteinuria (mg/24h) | 4.2 ± 0.8 | 82.2 ± 0.8 | <0.0001 | |
SBP (mmHg) | 131.1 ± 3.1 | 145.9 ± 4.7 | 0.0005 | |
eGFR (μl/min) | 2141 ± 81 | 629 ± 54 | <0.0001 | |
Weight (g) | 273 ± 4 | 271 ± 3 | 0.71 | |
Graft implantation | ||||
Survival | ||||
Survival implantation | 21 (23) | 22 (30) | ||
Patency grafts 24 h | 21 (21) | 20 (22) | ||
Patency end point | 20 (21) | 20 (20) |
Unpaired t-test.