Figure 1.

Identification of PRP-Exos. (a) The morphology of PRP-Exos was viewed by transmission electron microscope. (b) The particle size distribution of PRP-Exos was measured by nanoparticle tracking analysis; mean ± SD: 88.01 ± 21.01 nm. (c, d) Western blotting and quantitative analysis of PRP-Exos-specific markers CD63, flotillin and TSG101, and PRP-AS-specific markers CD41 and calnexin. ^***p< 0.001, ^**p < 0.01, ^*p < 0.05. PRP-Exos compared with PRP-AS. PRP platelet-rich plasma, PRP-AS activated supernatants of PRP, PRP-Exos exosomes derived from PRP