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. 2023 May 9;9(5):e15991. doi: 10.1016/j.heliyon.2023.e15991

Table 2.

Oncogenic Circular RNA and Long Non-Coding RNAs (lncRNA), Which Act as Competitive Endogenous RNA (ceRNA) for miR-372 (So-Called Sponging Effect) in Different Cancers.

RNA Malignancy Cell Lines
No. of Tissue Samples (Pair) Outcomes References
Normal Cancerous
KCNQ1OT1 Lung adenocarcinoma HEK293 A549,
H1975
50 larger tumor, advanced clinical stage, and a lower response rate to concurrent therapy [175]
OSER1-AS1 Hepatocellular Carcinoma N/A HepG2 and Hep3b 34 the proliferation, invasion and migration of HCC cells, and induced the
apoptosis
[176]
LncRNA HULC Hepatocellular Carcinoma N/A N/A 100 tumor node and metastases (TNM) higer stage,
HCC recurrence, intra-hepatic metastases, and Lower postoperative survival.
[[62], [171]]
PCAT-14 Hepatocellular Carcinoma LO2 Huh7,
HCCLM3, HepG2, SMMC7721, PLC5, and QGY7701
120 proliferation and invasion of hepatocellular carcinoma cells [66]
LncRNA HULC Osteosarcoma HfoB SAOS-2
U2OS
HoS
MG63
32 Cell proliferation, migration and invasion of OS cells [119]
Circ_0001721 Osteosarcoma HfoB1.19 U2OS
HoS
56 Tumor growth, proliferation, invasion, migration, EMT and promote cell apoptosis [118]

N/A: Not Applicable.