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. 2023 Mar 29;28(4):1402–1414. doi: 10.1038/s41380-023-02000-7

Table 1.

Summary of results showing pooled standardized mean differences (SMD; with Hedges’ g adjustment) between treatment and control arms for PBLIND measures of ADHD symptoms at the first assessment after the final CCT session. Significant values are bolded.

Effect size estimate Heterogeneity
Outcome Trials Included Study N Total N SMD 95%CI p I2 p*
ADHD Symptoms
ADHD Total All 14 631 0.12 −0.01 to 0.25 0.06 0 0.92
Semi-active control 13 561 0.13 −0.01 to 0.27 0.07 0 0.89
MED 6 324 0.16 −0.02 to 0.34 0.07 0 0.66
WMT 7 329 0.08 −0.12 to 0.27 0.43 0 0.93
MPT 5 226 0.11 −0.09 to 0.31 0.27 0 0.73
Children/adolescents 13 587 0.11 −0.02 to 0.24 0.08 0 0.89
Adults 1 na na na na na na
PBLIND assessed in intervention setting 5 167 0.22 −0.05 to 0.50 0.12 0 0.54
PBLIND not assessed in intervention setting 9 464 0.09 −0.05 to 0.23 0.20 0 0.94
Non-commercially funded 11 509 0.12 −0.02 to 0.26 0.09 0 0.78
Inattention All 14 631 0.17 0.02 to 0.33 0.03 0 0.93
Semi-active control 13 561 0.20 0.04 to 0.37 0.02 0 0.95
MED 6 258 0.29 −0.04 to 0.41 0.11 0 0.58
WMT 7 329 0.17 −0.05 to 0.39 0.13 0 0.86
MPT 5 226 0.12 −0.14 to 0.38 0.37 0 0.90
Children/adolescents 13 587 0.15 −0.02 to 0.31 0.08 0 0.95
Adults 1 na na na na na na
PBLIND in intervention setting 5 167 0.40 0.09 to 0.71 0.01 0 0.74
PBLIND not assessed in intervention setting 9 464 0.09 −0.09 to 0.28 0.32 0 0.99
Non-commercially funded 11 509 0.17 −0.01 to 0.34 0.06 0 0.81
Hyperactivity/ Impulsivity All 14 631 0.11 −0.04 to 0.27 0.16 0 0.99
Semi-active control 13 561 0.1 −0.07 to 0.27 0.24 0 0.98
MED 6 324 0.13 −0.10 to 0.35 0.27 0 0.99
WMT 9 405 0.11 −0.08 to 0.31 0.26 0 1.00
MPT 5 226 0.11 −0.15 to 0.28 0.41 0 0.44
Children/adolescents 13 587 0.12 −0.05 to 0.28 0.17 0 0.98
Adults 1 na na na na na na
PBLIND in intervention setting 5 167 0.15 −0.15 to 0.46 0.33 0 0.99
PBLIND not assessed in intervention setting 9 464 0.10 −0.09 to 0.28 0.29 0 0.86
Non-commercially funded 11 509 0.11 −0.07 to 0.29 0.22 0 0.93

ADHD attention-deficit/hyperactivity disorder, CI Confidence Intervals, I2 percentage of between-study variation across SMDs that is due to heterogeneity rather than chance, MED only a minority (i.e., <30%) of participants were receiving medication, MPT multi-process training, N sample size, PBLIND probably blinded, SMD Hedges’ g, WMT working memory training.

*p-values from Q – i.e., the chi-squared test statistic.