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. 2023 May 24;8:214. doi: 10.1038/s41392-023-01476-7

Fig. 4.

Fig. 4

In vivo MRSA-infected wound healing effect of Ag/BMO nanozyme. 1064 nm laser: 1 Wcm−2 for 10 min, H2O2: 3 mM, Ag/BMO NPs: 200 μg mL−1. If not otherwise specified, all NPs were dissolved in DI water for detection. a The change of wound areas for 7 d. P-value indicates the significant difference. **P < 0.01, ***P < 0.001. b, c Photographs of MRSA-infected wounds in various groups and the corresponding plates after treatments. Scar bar: 1 mm. d The quantified data of survival MRSA in infected wounds treated with different groups. P-value indicates the significant difference. **P < 0.01, ***P < 0.001. e ROS level of infected wounds (more red fluorescence indicated more ROS content). f H&E and Masson-stained tissues slices of infected wounds. g The percentage number of neutrophils and collagen index. h Levels of IL-6 and TNF-α. i Blood biochemistry and physiological index analysis for control and Ag/BMO groups