Table 2.

Classification accuracies grouped by promiscuous drugs. Classification statistics for predicting links from compounds whose pharmacological mechanism of action is known or at least reported in DrugBank and their protein targets. The results presented in this table are only for the testing set unseen during training. The table is grouped by the number of reported protein targets in DrugBank (more than 2, 2 or 1 target).

Metric	No active (Num. targets > 2)	Pharmacologically active (Num. targets > 2)	No active (2 targets)	Pharmacologically active (2 targets)	No active (1 target)	Pharmacologically active (1 target)
Accuracy score	0.835	0.835	0.869	0.869	0.863	0.863
F1 score	0.907	0.221	0.896	0.822	0.871	0.856
Precision score	0.995	0.127	0.873	0.861	0.799	0.950
Recall score	0.834	0.856	0.920	0.786	0.956	0.778