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CONSORT diagram. Hb, haemoglobin; AST, aspartate transaminase; ALT, alanine transaminase; HBsAg, hepatitis B surface antigen; CAR-T cells, chimeric antigen receptor T cells; DLT, dose-limiting toxicity; CR, complete response; PR, partial response; PD, progressive disease. ∗These patients received doses other than pre-specified three dose levels because of unexpected low CAR percentages caused by the early and premature manufacturing process.
