Table 1.
Differentially enriched (P ≤ 0.05) proteins between follicular (F) and luteal (L) phases
| Protein name | Protein description | F vs L adj. P-value* | F-cent PE** |
Putative function |
|---|---|---|---|---|
| ALDH3A2 | Aldehyde Dehydrogenase 3 Family Member A2 | 0.0114 | -1.46 | Detoxification of aldehydes |
| ATP1B2 | ATPase Na + /K + Transporting Subunit Beta 2 | 0.00654 | -2.23 | Ion transport, cell adhesion |
| B3GNT3 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 | 0.0358 | -2.17 | Metabolic processes |
| CDC6 | Cell Division Cycle 6 | 0.0025 | -1.85 | Cell cycle and division, DNA replication, mitosis |
| CDCP1 | CUB Domain Containing Protein 1 | 0.00486 | -1.26 | Cell adhesion, cell matrix remodelling |
| COMMD2 | COMM Domain Containing 2 | 0.000189 | -1.54 | Cell cycle, apoptosis, oncogenesis, adaptive immunity |
| CYP51A1 | Cytochrome P450 Family 51 Subfamily A Member 1 | 0.0111 | -1.67 | Steroid metabolism |
| DDHD2 | DDHD Domain Containing 2 | 0.0315 | -1.44 | Lipid metabolism |
| EFEMP1 | EGF Containing Fibulin Extracellular Matrix Protein 1 | 0.0275 | -1.48 | Cell adhesion, cell signalling |
| ENPP6 | Ectonucleotide Pyrophosphatase/ Phosphodiesterase 6 | 0.00549 | -2.05 | Lipid metabolism |
| EPHX1 | Epoxide Hydrolase 1 | 0.0407 | -2.68 | Aromatic hydrocarbons catabolism, detoxification |
| ERO1A | Endoplasmic Reticulum Oxidoreductase 1 Alpha | 0.0137 | -1.97 | Apoptosis, electron transport |
| F3 | Coagulation Factor III | 0.000491 | -2.94 | Haemostasis |
| GCNT2 | Glucosaminyl (N-Acetyl) Transferase 2 | 0.00231 | -1.53 | Metabolic processes |
| GM2A | GM2 Ganglioside Activator | 0.00322 | -3.03 | Lipid metabolism |
| HSD17B7 | Hydroxysteroid 17-Beta Dehydrogenase 7 | 0.00247 | -1.63 | Lipid metabolism, lipid and steroid biosynthesis |
| ILVBL | IlvB Acetolactate Synthase Like | 0.00785 | -1.65 | Lipid metabolism |
| INSR | Insulin Receptor | 0.0163 | -1.35 | Carbohydrate metabolism |
| IRF6 | Interferon Regulatory Factor 6 | 0.0194 | -1.23 | Epithelial cell proliferation |
| LAMTOR4 | Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 4 | 0.0159 | -1.59 | Cell signalling |
| MBOAT2 | Membrane Bound O-Acyltransferase Domain Containing 2 | 0.0392 | -1.37 | Lipid biosynthesis and metabolism |
| MFAP4 | Microfibril Associated Protein 4 | 0.00286 | -1.32 | Cell adhesion, intercellular interactions |
| MPP7 | MAGUK P55 Scaffold Protein 7 | 0.00126 | -1.41 | Cell polarity, tight junction |
| MSMO1 | Methylsterol Monooxygenase 1 | 0.00769 | -1.68 | Lipid and steroid metabolism and biosynthesis |
| MYO1C.1 | Myosin IC | 0.00000559 | 2.9 | Plasma membrane tension |
| OXTR | Oxytocin Receptor | 0.0283 | 2.48 | Cell signalling |
| PBDC1 | Polysaccharide Biosynthesis Domain Containing 1 | 0.0222 | 1.43 | Poorly understood |
| PDZK1IP1 | PDZK1 Interacting Protein 1 | 0.000453 | -1.81 | Poorly understood |
| PLAUR | Urokinase-type plasminogen activator receptor | 0.00308 | 2.14 | Cell signalling |
| RBP1 | Retinol Binding Protein 1 | 0.00709 | 1.57 | Metabolic processes, transport |
| RTN1 | Reticulon 1 | 0.00311 | -1.32 | Apoptosis, stress response, ER-Golgi transport |
| RTN3 | Reticulon 3 | 0.00173 | -1.36 | Apoptosis, stress response, ER-Golgi transport |
| S100A16 | S100 Calcium Binding Protein A16 | 0.0283 | 1.42 | Ion transport |
| SLC4A4 | Solute Carrier Family 4 Member 4 | 0.00000175 | 2.02 | Ion transport |
| SMG8 | SMG8 Nonsense Mediated MRNA Decay Factor | 0.0335 | -1.69 | Nonsense-mediated mRNA decay |
| TMBIM1 | Transmembrane BAX Inhibitor Motif Containing 1 | 0.00279 | -2 | Vascular remodelling |
| TMEM114 | Transmembrane Protein 114 | 0.000000185 | 2.93 | Poorly understood |
| TNC | Tenascin C | 0.00000587 | 3.36 | Cell adhesion |
| TOR2A | Torsin Family 2 Member A | 0.0117 | -1.44 | ATP binding |
| WFDC2 | WAP Four-Disulfide Core Domain 2 | 0.00654 | -1.8 | Broad range protease inhibitor |
| ZDHHC20 | Zinc Finger DHHC-Type Palmitoyltransferase 20 | 0.00499 | -1.65 | Metabolic processes |
* F vs L adj. P-value = luteal vs follicular adjusted P-value
** F-cent. PE = follicular centered protein expression