Table 2.
Impacts of sleep deprivation on peripheral corticosterone in studies evaluating female-only or female and male rodent cohorts. All reported effects describe changes from a control condition. Abbreviations: sleep deprivation (SleepDep), gonadectomy (GDX), ovariectomy (OVX), total sleep deprivation (TSD), paradoxical sleep deprivation (PSD).
| Length of SleepDep | SleepDep Method | Sample Collection Post-SleepDep |
Effect | Species and Strain | Citation |
|---|---|---|---|---|---|
| 6 h | TSD - Gentle Handling | Immediate (plasma) | Male: No effect Female: No effect | Mouse - Swiss Albino (5w) | Onaolapo et al. (2016) |
| 6 h | TSD - Gentle Handling | Immediate (feces) | Male: No effect Female: No effect | Mouse - C57Bl/6 J | Chiem et al. (2021) |
| 6 h | TSD - Gentle Handling | Immediate (plasma) | Males: No effect Males GDX: Increase Females: Increase Females OVX: Increase |
Rat - Wistar | Baratta et al. (2018) |
| 20 h | PSD - Modified Multiple Platform | +8 h (serum) | Male: Decrease Female: No effect | Mouse - C57Bl/6 J | Buban et al. (2020) |
| 22 h | PSD - Multiple Platform | Immediate (plasma) | Female: No effect | Mouse - BALB/c | Li et al. (2019)Front. |
| 24 h | Sleep Fragmentation - Sweeping Bar Chamber (24 h/day) | Immediate (serum) | Female: Increase | Mouse - C57Bl/6 J | Mishra et al. (2020) |
| 24 h | Sleep Fragmentation - Sweeping Bar Chamber | Immediate (serum) | Female: Increase | Mouse - C57Bl/6 J | Wheeler et al. (2021) |
| 48 h | PSD - Multiple Platform | Immediate (plasma) | Male: Increase Female: Increase | Mouse - BALB/c | Gonzalez-Castañeda et al. (2016) |
| 72 h | PSD - Modified Multiple Platform (20 h/day) | +8 h (serum) | Male: No effect Female: No effect | Mouse - C57Bl/6 J | Buban et al. (2020) |
| 72 h | PSD - Multiple Platform | Immediate (plasma) | Male: No effect Female: No effect OVX Female: No effect | Rat - Wistar | Hajali et al. (2012) |
| 96 h | PSD - Multiple Platform | Immediate (plasma) | Male: No effect Female: Increase | Mouse - BALB/c | Gonzalez-Castañeda et al. (2016) |
| 96 h | PSD - Multiple Platform | Immediate (serum) | Female: Increase | Rat - Wistar | Antunes et al. (2006) |
| 5 days | PSD - Multiple platform (22 h/day) | Immediate (plasma) | Female: Increase | Mouse - BALB/c | Li et al. (2019) |
| 8 days | TSD - Gentle Handling (4 h/day) | +15 h (serum) | Male: No effect Female: Increase | Mouse - CD1 | Murack et al. (2021) |
| 4 weeks | Sleep Fragmentation - Sweeping Bar Chamber (12 h/day) | Immediate (serum) | Female: Increase | Mouse - C57Bl/6 J | Wheeler et al. (2021) |
| 8 weeks | Sleep Fragmentation - Sweeping Bar Chamber (12 h/day) | +12 h (serum) | Female: Increase | Mouse - C57Bl/6 J | Mishra et al. (2020) |
| 8 weeks | Sleep Fragmentation - Sweeping Bar Chamber (12 h/day) | +7 days (serum) | Female: No effect | Mouse - C57Bl/6 J | Mishra et al. (2020) |
| 9 weeks | PSD - Modified Multiple Platform (8 h/day, 5 days/week) |
+3 days (serum) | Female: No effect | Mouse - Swiss Albino | Arora et al. (2021) |