Figure 1.

Percentage HIV risk-reduction estimates (y-axis) for HPTN 083 and HPTN 084 according to adherence as measured with TFV-DP at or near the seroconversion visit (x-axis). Point estimates and 95% CIs are included on the x-axis. For HPTN 083, person-years (number of infections), from left to right, were 274 (24), 290 (13), 316 (0), 1235 (0), and 1072 (2). For HPTN 084, person-years (number of infections), from left to right, were 738 (21), 505 (12), 350 (2), 291 (1), 58 (0). Abbreviations: BLQ, Below the Limit of Quantification; CI, confidence interval; DBS, dried blood spot; HIV, human immunodeficiency virus; HPTN, HIV Prevention Trials Network; TFV-DP, tenofovir diphosphate.