Table 1.
Characteristics of the study population
| Total n = 720 | CDR = 0 n = 343 | CDR = 0.5 n = 377 | p-value | ||
|---|---|---|---|---|---|
| TP0 | N (n, % male) | 720 (445, 61.81) | 343 (253, 73.76) | 377 (192, 50.93) | <0.0001 |
| Age, mean (S.E.) | 70.04 (0.17) | 70.03 (0.24) | 70.05 (0.24) | 0.9415 | |
| BMI, mean (S.E.) | 26.49 (0.17) | 26.1 (0.24) | 26.84 (0.23) | 0.0256 | |
| MMSE, mean (S.E.) | 29.26 (0.05) | 29.62 (0.04) | 28.94 (0.09) | <0.0001 | |
| CDR-SoB, mean (S.E.) | 0.91 (0.02) | 0.44 (0.02) | 1.34 (0.03) | <0.0001 | |
| MDD, % (n) | 4.58 (33) | 5.25 (18) | 3.98 (15) | 0.5255 | |
| Hypertension, % (n) | 62.26 (447) | 56.14 (192) | 67.82 (255) | 0.0016 | |
| Diabetes, % (n) | 15.86 (114) | 12.83 (44) | 18.62 (70) | 0.0433 | |
| Dyslipidemia, % (n) | 54.03 (389) | 48.69 (167) | 58.89 (222) | 0.0076 | |
| Education level, % low (n) | 61.53 (443) | 56.27 (193) | 66.31 (250) | 0.0071 | |
| Never smoker, % (n) | 41.82 (299) | 46.76 (159) | 37.33 (140) | 0.0122 | |
| Former smoker, % (n) | 44.76 (320) | 41.18 (140) | 48 (180) | 0.0617 | |
| Current smoker, % (n) | 13.43 (96) | 12.06 (41) | 14.67 (55) | 0.0378 | |
| Statins treatment, % (n) | 14.7 (106) | 11.6 (40) | 17.5 (66) | 0.0292 | |
| TP1 | MMSE, mean (S.E.) | 28.98 (0.05) | 29.24 (0.06) | 28.75 (0.09) | <0.0001 |
| CDR SoB, mean (S.E.) | 0.86 (0.03) | 0.65 (0.04) | 1.06 (0.05) | <0.0001 | |
| CDR = 0, % (n) | 48.04 (245) | 65.99 (163) | 31.18 (82) | <0.0001 | |
| CDR = 0.5, % (n) | 51.37 (262) | 33.2 (82) | 68.44 (180) | <0.0001 | |
| CDR =1, % (n) | 0.59 (3) | 0.81 (2) | 0.38 (1) | <0.0001 |
Group comparisons between CDR = 0 and CDR = 0.5 groups were performed using Mann–Whitney U-Test for continuous variables and Chi-square tests for categorical variables. Significant p-values are shown in bold. The number of study participants within each groups is denoted n.