TABLE 1.
Clinical Trial and Location |
Year Clinical Trial Established |
Minimum Number of Cryopreserved Embryos |
PGT-A Required |
Renal Pathology Excluded |
Age |
---|---|---|---|---|---|
Baylor University Medical Center Dallas, Texas | November 2015 | At least 2 d 5–6 euploid blastocysts of satisfactory quality, increased to 4 good-quality euploid blastocysts midway through study | Yes | Exclude individuals with renal malformations (not including single kidney) | 20-35 at the time of IVF |
Cleveland Clinic Cleveland, Ohio | October 2015 | 6 | No | Exclude individuals with presence of low-lying pelvic kidney(s) | 21-45 (embryos produced between age 21-39) |
Institute for Clinical and Experimental Medicine Prague, Czechia | October 2015 | 10 | No | Not specified | 18-40 |
Hammersmith Hospital, Imperial College NHS Trust London, UK | February 2019 | ≥ 10 embryos | Not specified | Exclude individuals with renal pathology | 24-38 (or 40 if eggs frozen <38) |
University of Pennsylvania, Philadelphia, Pennsylvania | November 2017 | ≥ 2 high quality blastocysts | No | Exclude individuals with renal abnormalities (including single kidney or pelvic kidneys) | 21-40 |
IVF indicates in vitro fertilization; PGT-A, preimplantation genetic testing for aneuploidy.