Table 2.
History of falls versus no previous falls |
|||
---|---|---|---|
Crude HR (95%CI) | Age- and sex-adjusted HR (95%CI)* | Multivariable adjusted HR (95%CI)** | |
Primary outcomes | |||
Stroke/SE | 1.78 (1.64–1.93) | 1.60 (1.48–1.73) | 1.06 (0.97–1.16) |
Ischemic stroke | 1.95 (1.76–2.17) | 1.63 (1.47–1.82) | 1.07 (0.96–1.20) |
All-cause mortality | 3.01 (2.90–3.12) | 2.06 (1.99–2.14) | 1.11 (1.06–1.15) |
Major bleeding | 1.75 (1.65–1.85) | 1.59 (1.50–1.68) | 1.07 (1.01–1.14) |
Intracranial bleeding | 1.65 (1.47–1.85) | 1.65 (1.47–1.85) | 1.30 (1.16–1.47) |
Gastrointestinal bleeding | 1.79 (1.65–1.94) | 1.55 (1.43–1.68) | 1.02 (0.93–1.11) |
Secondary outcomes | |||
New fall | 3.18 (3.04–3.32) | 2.35 (2.25–2.46) | 1.63 (1.55–1.71) |
Table 2: Crude, age- and sex-adjusted, and multivariable adjusted hazard ratios with 95% confidence intervals of outcomes compared between anticoagulated AF patients with versus without a history of falls using Cox proportional hazard regression models.
Adjusted for age and sex. ** Adjusted for age, sex, OAC type, baseline comorbidities and medication history with backward elimination. AF: atrial fibrillation; CI: confidence interval; HR: hazard ratio; OAC: oral anticoagulant; SE: systemic embolism.