TABLE 3.
Isolation of infectious HSV-1(F) or of recombinant viruses R7538(P−/O−) and R7543(P−/O−)R from murine trigeminal ganglia
| Virus | PFU/ganglion (1,000)a on day:
|
|
|---|---|---|
| 3 | 5 | |
| HSV-1(F) | 27 ± 4.2 | 138 ± 23 |
| R7538(P−/O−) | 9.0 ± 2.3 | 0.32 ± 0.12 |
| R7543(P−/O−)R | 29 ± 9.3 | 77 ± 16 |
a
Average counts of plaques ± standard error appearing in flasks containing Vero cells, which were infected with 10-fold dilutions of trigeminal ganglion homogenates (20 ganglia total per virus), harvested at the indicated days after ocular infection.