Table 6. Vascular risk factor associations with CVD.
Risk factor | Age | Neuropathologic AD | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Cerebrovascular lesion | Vascular risk factors | OR | p-value | OR | p-value | OR | p-value | |||
Infarcts, any | Single | 3.31 | <0.001 | 1.20 | 0.001 | 0.78 | 0.23 | |||
Multiple | 2.25 | <0.001 | 1.23 | <0.001 | 0.77 | 0.21 | ||||
Moderate/severe arteriosclerosis | Single | 3.02 | <0.01 | 1.28 | <0.01 | 3.64 | 0.001 | |||
Multiple | 1.89 | 0.05 | 1.33 | <0.001 | 2.07 | 0.01 | ||||
Moderate/severe CAA | Single | 0.90 | 0.56 | 1.43 | <0.001 | 8.63 | <0.001 | |||
Multiple | 1.10 | 0.57 | 1.40 | <0.001 | 8.46 | <0.001 | ||||
Any single lesion | Single | 0.86 | 0.37 | 1.17 | <0.01 | 2.56 | <0.001 | |||
Multiple | 0.87 | 0.38 | 1.16 | <0.01 | 2.57 | <0.001 | ||||
CVD | Single | 2.33 | 0.001 | 1.55 | <0.001 | 2.81 | <0.001 | |||
Multiple | 2.01 | 0.001 | 1.57 | <0.001 | 2.75 | <0.001 |