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Table 6. Vascular risk factor associations with CVD.

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Risk factor Age Neuropathologic AD
Cerebrovascular lesion Vascular risk factors OR p-value OR p-value OR p-value
Infarcts, any Single 3.31 <0.001 1.20 0.001 0.78 0.23
Multiple 2.25 <0.001 1.23 <0.001 0.77 0.21
Moderate/severe arteriosclerosis Single 3.02 <0.01 1.28 <0.01 3.64 0.001
Multiple 1.89 0.05 1.33 <0.001 2.07 0.01
Moderate/severe CAA Single 0.90 0.56 1.43 <0.001 8.63 <0.001
Multiple 1.10 0.57 1.40 <0.001 8.46 <0.001
Any single lesion Single 0.86 0.37 1.17 <0.01 2.56 <0.001
Multiple 0.87 0.38 1.16 <0.01 2.57 <0.001
CVD Single 2.33 0.001 1.55 <0.001 2.81 <0.001
Multiple 2.01 0.001 1.57 <0.001 2.75 <0.001