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Table 5. Age and AD associations with CVD .

(No legend)

Age Neuropathologic AD
Lesion Effect 95% CI p-value Effect 95% CI p-value
Infarct, large 1.25 (1.11, 1.41) <0.001 0.98 (0.60, 1.60) 0.94
Infarct, lacunar 1.26 (1.13, 1.42) <0.001 0.76 (0.48, 1.20) 0.24
Infarct, micro 1.20 (1.08, 1.33) <0.001 1.28 (0.85, 1.94) 0.24
Hemorrhage 0.94 (0.80, 1.09) 0.41 1.06 (0.53, 2.13) 0.86
Moderate/severe arteriolosclerosis 1.21 (1.13, 1.29) <0.001 1.29 (0.98, 1.72) 0.07
Moderate/severe CAA 1.12 (1.05, 1.19) <0.001 7.42 (5.61, 9.82) <0.001
Any single lesion 1.05 (0.99, 1.11) 0.09 2.29 (1.82, 2.89) <0.001
CVD (multiple) 1.29 (1.19, 1.39) <0.001 2.25 (1.65, 3.06) <0.001