Skip to main content

Table 3.

Hypothetical correlation between PART and AD. From [253].

No AD/no PART Asymptomatic PART p-preAD NFT-predominant dementia (symptomatic PART) Symptomatic AD
Aβ phase 0 0–2 1–5 0–2 3–5
Braak-NFT-stage 0 I–IV 0–VI III, IV III–VI
Degree of AD pathology No AD No or low AD Low–high AD No AD or low Intermediate–high AD
Clinical signs of dementia or cognitive decline No No No Yes Yes

PART vs. AD: symptomatic PART and symptomatic AD can be distinguished by Aβ pathology. Asymptomatic PART and p-pre-AD overlap in those cases with initial Aβ pathology (Aβ phases 1, 2)