AAV seroprevalence in study participants based on ambulatory status. (A) Overall seroprevalence rates for AAV2, AAV8, AAV9, and AAVrh74 NAbs in the study cohort grouped based on ambulatory status: ambulatory, n = 48, and nonambulatory, n = 46, for AAV2 and AAV9 analysis. Ambulatory, n = 43, and nonambulatory, n = 43, for AAV8 and AAVrh74 analysis. (B) Average NAb titers for indicated serotypes for ambulatory and nonambulatory participants. Note that only participant samples with NAb titers >1:5 were used for the analysis; *p < 0.05 based on unpaired Student's t-test. All other comparisons are not significant.