Table 1.
Mean and standard deviation of demographic characteristics, Viral loads and CD4 + T cell counts at baseline and upon virologic failure according to the HIV resistance profile
| N | Age (years)a | Males n(%) | Females n(%) | Viral Load at virologic failurea | CD4 at virologic failurea | Baseline Viral Loada | Baseline CD4a | |
|---|---|---|---|---|---|---|---|---|
| Wild Type HIV | 65 | 35.7(10.27) | 42(73.68) | 15(26.32) | 4.91(5.263) | 438(332.5) | 5.66(6.112) | 391(359) |
| TL + D RAMS | 2 | 34.0(4.243) | 2(100.00) | 0(0.00) | 5.35(5.413) | 53.5(30.41) | 6.12(6.112) | 45.5(55.86) |
| TL RAMS | 6 | 37.2(15.79) | 3(50.00) | 3(50.00) | 5.44(5.662) | 175(172.6) | 5.87(6.029) | 161(170.8) |
| Major INRAMS | 7 | 37.9(14.35) | 5(71.43) | 2(28.57) | 5.01(5.145) | 238(218.4) | 5.73(5.935) | 184(211.2) |
| Minor INRAMS | 18 | 33.6(10.58) | 12(75.00) | 4(25.00 | 5.17(5.411) | 281(237.9) | 5.77(5.84) | 179(178.85) |
| NRTI RAMS | 15 | 35.1(11.43) | 10(71.43) | 4(28.57) | 5.50(5.853) | 221(188.7) | 5.90(6.015) | 207(193.8) |
| NNRTI RAMS | 16 | 35.5(12.29) | 9(69.23) | 4(30.77) | 5.17(5.595) | 356(200.6) | 5.35(5.686) | 304(149.8) |
| PI RAMS | 6 | 38.8(10.43) | 4(80.00) | 1(20.00) | 4.93(5.077) | 216(176.8) | 5.28(5.286) | 212(158.2) |
| Total | 113b | 36.1(10.77) | 73(73.00) | 27(27.00) | 5.13(5.55) | 365.9(294.1) | 5.67(6.034) | 323.2(305.6) |
The total n of 113 is less than the sum of the n’s in the categories as there were many cases that had multiple categories of RAMs
TL Tenofovir/lamivudine, D Dolutegravir, RAM Resistance-associated mutations, INRAM Integrase resistance-associated mutations, NRTI Nucleoside reverse transcriptase inhibitor, NNRTI Non-nucleoside reverse transcriptase inhibitor, PI Protease inhibitors
aMean(std. dev.)
bone sample failed in the RT and protease PCR amplification