Table 5.

Use of cut off values of individual factors and combined score for predicting unfavorable outcome of patients with CM.

Variable	Cut-off value	Pvalue	AUC	Sensitivity,	Specificity,	Accuracy,
CSF glucose	≤ 1.71 mmol/L	0.029	0.599	50.0%	76.7%	60.3%
GCS score	≤ 14	<0.001	0.622	26.0%	98.3%	53.8%
Age at onset	>45 yrs	0.018	0.610	70.8%	48.3%	62.2%
ventriculoperitoneal shunt placement	presented	0.003	0.574	19.8%	95.0%	48.7%
Immunocompromised condition	presented	<0.001	0.620	40.6%	83.3%	57.1%
Combined score	>2.67	<0.001	0.815	69.8%	78.3%	73.1%

CM, cryptococcal meningitis; CSF: cerebrospinal fluid; AUC: area under the curve