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Sequence space of the SA8 family (A) and disulphide connectivities of venom SA8 (B) and ShK (C). A The SA8 family (yellow) forms a distinct cluster from the ShKT domains of ShK-like (red) and CRISP (black) peptides [27]. B The C1–C5, C2–C6, C3–C4 disulphide connectivity of the mature venom SA8 peptide from T. stephensoni. C The C1–C6, C2–C4, C3–C5 disulphide connectivity of ShK toxin from S. helianthus
