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Increased sequencing depth across amplicons and increased genome coverage in SARS-CoV-2 BA.1 samples amplified with V4.1 primers. Analysis of 59 BA.1 samples with V4 and V4.1 primers. (a) Median coverage across amplicons 10, 23, 27, 76, 79, 88, 89 and 90 with V4 (blue) and V4.1 (orange). (b) Percentage genome coverage at >50× coverage of all 59 SARS-CoV-2 BA.1 samples. Assemblies with V4 primers are in blue, and V4.1 primers in orange.
