Figure 2:

Cartilage tissue engineering results from the study of Mauck et al. [55]. (a) Constructs did not change significantly in size over 6 weeks in culture. (b) Equilibrium Young’s modulus, (c) mass fraction $w^{GAG}$ of proteoglycan content, and (d) mass fraction $w^{COL}$ of collagen content all increased significantly over time in culture. The mass fraction of interstitial fluid in these porous constructs can be deduced from $w^f\approx 1-w^{AG}-w^{GAG}-w^{COL}$, as collagens and proteoglycans make up the vast majority of solid matrix constituents in cartilage, and the mass fraction of the agarose scaffold, $w^{AG}\approx 0.02$, remained fixed over time in culture.