Antibodies | |||
---|---|---|---|
Specific single-chain antibody fragments | Fibril surface | 2nd nucleation ↓↓ | 56 |
Aducanumab (murine) | Fibril surface | 2nd nucleation ↓↓ | 15 |
Gantenerumab (murine) | Fibril-ends | Elongation ↓↓ | 15 |
Bapineuzumab (murine) | Fibril-ends | Elongation ↓↓ | 15 |
Solanezumab (murine) | Monomers | Primary nucleation ↓↓ | 15 |
Only determined by fit analysis and not confirmed by seeding experiments.