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. 2023 Apr 26;51(2):871–886. doi: 10.1042/BST20220494

Figure 3. The NPC during nucleocytoplasmic transport.

Figure 3.

Upper: Molecular representation of the nuclear transport mechanism, at the scale of NTRs and non-specific macromolecules in the proximity of FG repeats. Middle Left: Disposition of FG repeats, showing different potential behaviors. Middle Right: Representation of an NPC with transiting macromolecules, to approximate scale and stoichiometry. Lower: Diagram of two adjacent FG repeats (green) interacting in solvent water (red/white) with a cognate interaction site (orange) on an NTR (blue).