Figure 3. Region-wise laterality of cell densities in C57BL/6J.
(A) Laterality differences in density (all C57BL/6J brains n = 369) shown for all regions whose volume >0.05 mm3 (excluding layers 1 and 6b) resulting in 559 regions. Regions are sorted by their bias to the left. Red and blue dots show layer 2/3 and layer 5/6a, respectively. Upper inset shows the distribution of layer 2/3 regions and layer 5/6a in red and blue lines, respectively. (B) Scatter plot of the density of the left vs. right hemisphere for parasubiculum (PAR). Each dot corresponds to one brain. Vertical and horizontal cyan lines correspond to the left and right median values, respectively. The dashed dotted line is equi-density value and the dashed line corresponds to a 10% offset by the median of the left density. The inset shows an analogous scatter plot for volume, with no observed lateral bias. (C) Percentage of brains with tendency for left or right hemisphere density across cortical areas (blue, left > right; orange, right > left). (D) Scatter plots of the density of the left vs. right hemisphere for visceral area layers 2/3, 4, 5, and 6A.
Figure 3—figure supplement 1. Volcano plots showing region-wise comparison of left vs. right hemispheres in C57BL/6J and FVB.CD1.
