TABLE 3.

DSA and Banff scores at index biopsy

			Index biopsy			Follow-up biopsy
			Responder	Nonresponder	P	Responder	Nonresponder	P
DSA at index biopsy	Against class I(%)		14 (21)	39 (33)	0.08	7 (11)	26 (22)	0.051
	Against class II (%)		33 (50)	78 (67)	0.03	27 (41)	60 (51)	0.18
	Sum MFI class I		2998 ± 7948	3873 ± 5184	0.64	1938 ± 4020	2646 ± 3699	0.66
	Sum MFI class II		12 082 ± 14 109	12 769 ± 13 777	0.81	8821 ± 9918	11 777 ± 13 362	0.31
Banff scores	g	0	4 (6)	5 (4)	0.005	51 (77)	3 (3)	<0.001
		1	29 (44)	33 (28)		15 (23)	38 (33)
		2	26 (39)	40 (35)		0	48 (41)
		3	7 (11)	39 (34)		0	28 (24)
	ptc	0	14 (21)	16 (14)	0.04	58 (88)	13 (11)	<0.001
		1	37 (56)	52 (44)		8 (12)	68 (58)
		2	15 (23)	44 (38)		0	33 (28)
		3	0	5 (4)		0	3 (93)
	Mean MVI (g+ptc)		2.56 ± 0.89	3.29 ± 1.12	<0.001	0.35 ± 0.48	3.08 ± 1.0	<0.001
	C4d	0	57 (86)	86 (74)	0.15	62 (94)	90 (77)	0.01
		1	1 (2)	2 (2)		2 (3)	3 (3)
		2	3 (5)	5 (4)		0	6 (5)
		3	5 (8)	24 (21)		2 (3)	18 (15)
	cg	0	41 (65)	48 (43)	0.03	51 (77)	52 (45)	<0.001
		1	11 (18)	27 (24)		6 (9)	24 (21)
		2	5 (8)	21 (19)		4 (6)	21 (18)
		3	6 (10)	17 (15)		5 (8)	19 (16)
	Mean sum chronicity scores(cg+cv+ct+cv)		3.23 ± 2.20	4.12 ± 2.25	0.009	3.26 ± 2.09	4.12 ± 2.41	0.02
Treatment	IVIG		63 (96)	111 (95)	0.86
	Steroids		63 (96)	111(96)	0.86
	Rituximab		30 (46)	69 (59)	0.08
	Plasmapheresis		4 (6)	3 (3)	0.24

Bold values indicate statistically significant value with P <0.05.

cg, transplant glomerulopathy; ct, tubular atrophy; cv, fibrous intimal thickening; DSA, donor-specific antibody; g, glomerulitis; MFI, mean fluorescent intensity; MVI, microvascular inflammation; ptc, peritubular capillaritis.